Theoretical labelling pattern of the C
pool (GAP and PYR) derived from 99% [1-13C] glucose depending on activities in the carbon core metabolism. The three major routes for glucose catabolism are presented: glycolysis (solid lines), the pentose phosphate pathway (dashed lines) and the Entner-Doudoroff pathway (dotted lines). White circles represent unlabelled (12C) carbon whereas black circles indicate labelled (13C) carbon. The numbers reflect the position of the carbon atom within the molecule. Ala: alanine; G6P: glucose 6-phosphate; 6PG: 6-phosphogluconate; KDPG: 2-keto-3-deoxy-6-phosphogluconate; F6P: fructose 6-phosphate; R5P: ribose 5-phosphate; GAP: glyceraldehyde 3-phosphate; PYR: pyruvate.