TY - JOUR AU - Jana, Bimal AU - Panja, Subrata AU - Saha, Swati AU - Basu, Tarakdas PY - 2009 DA - 2009/01/29 TI - Mechanism of protonophores-mediated induction of heat-shock response in Escherichia coli JO - BMC Microbiology SP - 20 VL - 9 IS - 1 AB - Protonophores are the agents that dissipate the proton-motive-force (PMF) across E. coli plasma membrane. As the PMF is known to be an energy source for the translocation of membrane and periplasmic proteins after their initial syntheses in cell cytoplasm, protonophores therefore inhibit the translocation phenomenon. In addition, protonophores also induce heat-shock-like stress response in E. coli cell. In this study, our motivation was to investigate that how the protonophores-mediated phenomena like inhibition of protein translocation and induction of heat-shock proteins in E. coli were correlated. SN - 1471-2180 UR - https://doi.org/10.1186/1471-2180-9-20 DO - 10.1186/1471-2180-9-20 ID - Jana2009 ER -