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Table 3 Association between antibiotic resistance and pherotype.

From: Pherotypes are driving genetic differentiation within Streptococcus pneumoniae

Antibiotic CSP-1 CSP-2 OR (95% CI)a FDRb
  Resistant Susceptible Resistant Susceptible   
Penicillinc, d 92 249 21 121 2.13 (1.24;3.78) 0.012
Erythromycin 32 309 16 126 0.82 (0.42;1.65) 0.611
Clindamycin 22 319 16 126 0.54 (0.26;1.15) 0.141
Tetracyclined 18 323 20 122 0.31 (0.16;0.70) 0.010
Chloramphenicold 5 336 9 133 0.22 (0.05;0.75) 0.013
Co-trimoxazoled 89 252 17 125 2.59 (1.45;4.86) 0.005
Cefuroximed 68 272 12 129 2.68 (1.38;5.64) 0.010
  1. a Odds ratio (OR) measures the strength of the association between a pherotype and resistance to a particular antibiotic. In each case, if OR is significantly > 1, CSP-1 is associated with resistance to that antibiotic and if OR is significantly < 1 this means that CSP-2 is associated with resistance to that particular antibiotic.
  2. b Correction for multiple testing performed by the false discovery rate method (FDR)
  3. c p < 0.05 after FDR correction.
  4. d Both penicillin intermediate and fully resistant isolates were considered resistant for this analysis.