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Table 3 Antimicrobial compounds having significantly lower MICs in hop-resistant isolatesa.

From: Susceptibility of Pediococcus isolates to antimicrobial compounds in relation to hop-resistance and beer-spoilage

Antimicrobial compound Median and Distribution of MIC (μg/ml) p-valueb
  Hop-resistant Hop-sensitive  
Ampicillin 0.25 (0.12-4) 1 (0.12-4) < 0.05
Ciprofloxacin 2 (0.5-NRc) 4 (0.5-NR) < 0.05
Gatifloxacin 1 (0.5-8) 4 (1-NR) < 0.05
Penicillin 0.12 (0.06-NR) 2 (0.06-NR) < 0.02
Rifampin 0.5 (0.5-2) 1 (0.5-NR) < 0.05
  1. a Hop-resistance is as determined by the hop-gradient agar plate with ethanol method.
  2. b p-value corresponds to U-test statistic as derived from the non-parametric Mann-Whitney U-test which is designed to examine whether two samples of observations came from the same distribution.
  3. c NR; MIC not reached, isolate could grow at highest concentration of antibiotic tested.