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Table 3 Antimicrobial compounds having significantly lower MICs in hop-resistant isolatesa.

From: Susceptibility of Pediococcus isolates to antimicrobial compounds in relation to hop-resistance and beer-spoilage

Antimicrobial compound

Median and Distribution of MIC (μg/ml)

p-valueb

 

Hop-resistant

Hop-sensitive

 

Ampicillin

0.25 (0.12-4)

1 (0.12-4)

< 0.05

Ciprofloxacin

2 (0.5-NRc)

4 (0.5-NR)

< 0.05

Gatifloxacin

1 (0.5-8)

4 (1-NR)

< 0.05

Penicillin

0.12 (0.06-NR)

2 (0.06-NR)

< 0.02

Rifampin

0.5 (0.5-2)

1 (0.5-NR)

< 0.05

  1. a Hop-resistance is as determined by the hop-gradient agar plate with ethanol method.
  2. b p-value corresponds to U-test statistic as derived from the non-parametric Mann-Whitney U-test which is designed to examine whether two samples of observations came from the same distribution.
  3. c NR; MIC not reached, isolate could grow at highest concentration of antibiotic tested.