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Table 2 Growth on Czapek medium supplemented with inhibitors of melanin biosynthesis

From: Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia

Strain or isolate number

Control

Tricyclazole

Pyroquilon

Fenoxanil

Reference strains

    

   CBS 113.26

31.7 ± 1.52

30 ± 4.36

29.3 ± 2.08

32.3 ± 0.58

   IHEM 18963

32 ± 2

31.7 ± 1.15

28 ± 1*

31.2 ± 0.28

Mutant isolates

    

   IHEM 2508

33.7 ± 0.58

32 ± 2

31 ± 1*

33.3 ± 1.15

   IHEM 9860

31.7 ± 1.15

30.7 ± 1.53

34 ± 1.73

25.3 ± 1.53*

   IHEM 15998

35.7 ± 0.58

34 ± 1.73

35 ± 2.64

27.7 ± 0.58*

  1. Experiments were performed in triplicate and results are expressed as mean diameter (mm) of the colonies (± standard deviation) after 72 hours of incubation at 37°C. *indicates statistically significant difference between control and inhibitor of melanin biosynthesis (unpaired Student's t-test; P < 0.05).