Figure 3

Effects of A5/L phages on the circulating blood cell composition in cyclophosphamide-treated and S. aureus -infected mice. B – bands, S – segments, E – eosinophils, L – lymphocytes, M – monocytes; I – immature forms. Mice were given CP (350 mg/kg b.w.). After four days 1 × 10⁶ A5/L phages and 5 × 10⁶ S. aureus were administered. Samples of blood were taken on day 0, just before administration of CP (Control), 4 days after administration of CP, just before administration of phages and bacteria (day 4) and at 24 h following infection (day 5). The results are presented as the mean value of 5 mice per group. Statistics (day 5): Bands: CP⁺P^-B⁺ vs CP⁺P⁺B⁺ P = 0.0261 (ANOVA; P = 0.0000); Segments: CP^-P^-B⁺ vs CP⁺P^-B⁺ P = 0.0003; CP⁺P^-B^- vs CP⁺P^-B⁺ P = 0.0489 (ANOVA; P = 0.0000); Eosinophils: all crucial comparisons NS (ANOVA); Lymphocytes: CP⁺P^-B⁺ vs CP⁺P⁺B⁺ P = 0.0003; CP⁺P^-B^- vs CP⁺P^-B⁺ P = 0.0042 (ANOVA; P = 0.0000); Monocytes: all crucial comparisons NS (ANOVA); Immature forms: CP^-P^-B⁺ vs CP⁺P^-B⁺ P = 0.0498 (ANOVA; P = 0.0000).