Table 2 Arsenic-induced or repressed proteins in T. arsenivorans and Thiomonas sp. 3As.

Energy and carbon metabolism

Calvin Cycle

rbcL

Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit

+

-

cbbFC1

Fructose-1,6-bisphosphatase

+

0

cbbA1

Fructose biphosphate aldolase

0

-

TCA cycle/reductive carboxylate cycle

icd

Isocitrate dehydrogenase, specific for NADP+

+

0

Glyoxylate and dicarboxylate metabolism

aceB

Malate synthase A

+

0

gltA

Citrate synthase

+

0

aceA

Isocitrate lyase

0

+

/

Tartrate dehydrogenase/decarboxylase (TDH) (D-malate dehydrogenase [decarboxylating])

0

+

Glycolyse/gluconeogenesis

ppsA

Phosphoenolpyruvate synthase

+

-

aceE

Pyruvate dehydrogenase E1 component

+

-

lpdA

Dihydrolipoyl dehydrogenase (Pyruvate dehydrogenase E3 component)

+

0

eno2

Enolase

0

-

Thiosulfate oxydation

/

Putative sulfur oxidation protein SoxB

0

-

Cellular processes, transport and binding proteins

Arsenic resistance

arsA2

Arsenical pump-driving ATPase

+

0

arsC1

Arsenate reductase

0

+

High temperature resistance

hldD

ADP-L-glycero-D-manno-heptose-6-epimerase

+

0

General stress

groL

GroEL, 60 kDa chaperonin

+

0

Other stresses

ahpF

Alkyl hydroperoxide reductase subunit F

0

-

Twitching/motility/secretion

/

Putative methyl-accepting chemotaxis protein

0

-

/

Putative type IV pilus assembly protein PilM

0

-

Cell division

/

Putative cell division protein

0

-

DNA metabolism, transcription and protein synthesis

DNA bending, supercoiling, inversion

gyrA

DNA gyrase subunit A

+

-

RNA degradation

pnp

Polyribonucleotide nucleotidyltransferase

+

-

Protein synthesis

fusA

Elongation factor G (EF-G)

+

0

tufA

Elongation factor Tu

+

0

rpsB

30S ribosomal protein S2

+

0

rpsA

30S ribosomal protein S1

0

-