Table 4 Rifampin resistance of M. tuberculosis recombinant clones
|  | MIC of rifampin (μg/ml) of M. tuberculosis recombinant clones carrying mutated rpoB gene controlled by: | |||
|---|---|---|---|---|
mutated amino acid of RpoB | PrpoB | Phsp65 | ||
| Â | H37Ra | KL1936 | KL463 | H37Ra |
H526D | 50 | 50 | 50 | 50 |
D516V | 25 | 25 | 25 | 25 |
Q510H; D516Y | 1,5 | 6,2 | 6,2 | 6,2 |
S512I; D516G | 6,2 | 6,2 | 6,2 | 6,2 |
Q513L | 6,2 | 12,5 | 50 | 6,2 |
M515I; D516Y | 6,2 | 6,2 | 6,2 | 6,2 |
D516Y | 3,1 | 6,2 | 3,1 | 6,2 |
S531L | 50 | 50 | 50 | 50 |