Assessment of decorin-binding protein A to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection

Table 1 Assessing infectivity of BbKH500 in needle-challenged C3H/HeJ mice.

	Inoculation dose (bacteria/inoculation)
Time post-infection (wks)	10^4a	10^5a	10^6a	10^7a
5	0/10	0/17	0/10	5/5
10	ND	3/17	2/10	ND
14^b	0/5	2/10	4/10	5/5
Cumulative results	0/15	5/27	6/20	10/10

^a Mice were needle infected with varying concentrations of bacteria. Infection rates were assessed at the noted timepoints by culturing BbKH500 from ear-punch biopsies.
^b Mice from 14 week timepoint represent groups distinct from the 5- and 10-week groups.

ISSN: 1471-2180