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Table 2 Comparison of accuracy of various assays for detection of H. pylori infection

From: Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history

Assays

Sensitivity

Specificity

Youden's index1

23S rRNA PCR2

83.4% (373/447)

75.5% (114/151)

0.59

13C-UBT3

94.9% (373/393)

70.8% (114/161)

0.66

ELISA4

95.2% (373/392)

63.7% (114/179)

0.59

  1. 1: defined as "sensitivity + specificity - 1";
  2. 2: both 13C-UBT and ELISA were positive or negative for comparison;
  3. 3: both PCR and ELISA were positive or negative for comparison;
  4. 4: both PCR and 13C-UBT were positive or negative for comparison.
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BMC Microbiology

ISSN: 1471-2180

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