Table 1 Comparisons of sex, age, H. pylori infection, and mutations of the 23S rRNA gene between subjects with and without CLR use history

CLR use history

-

-

+

Case No.

310

307

153

770

Sex ratio (M:F)

1:1.00

1:1.13

1:0.82

1:1.01

Age (yrs) (Mean ± SD)

45.3 ± 8.4

45.0 ± 8.4

45.7 ± 8.6

45.2 ± 8.5

H. pylori-positive rate in 2003 (%)

¹³C-UBT

90.6 (280/309)

54.1¹ (166/307)

53.3 (81/152)

68.1 (527/768)

ELISA

92.5 (283/306)

62.1¹ (185/298)

44.1² (64/145)

71.0 (532/749)

23S rRNA

83.9 (260/310)

51.1¹ (157/307)

26.8² (41/153)

59.5 (458/770)

Proportion of 2143G-positive H. pylori (%)

Total CLR^r

13.8 (36/260)

10.2 (16/157)

31.7³ (13/41)

14.2 (65/458)

CLR^{r & s}

9.6 (25/260)

6.4 (10/157)

14.6 (6/41)

9.0 (41/458)

Proportion of MboII-RFLP-positive H. pylori (%)

2222CTTCA

0.4 (1/260)

1.9 (3/157)

4.9⁴ (2/41)

1.3 (6/458)

2081GAAG

1.9 (5/260)

1.3 (2/157)

14.6⁵ (4/41)

2.4 (11/458)