Disease group | Number of individuals per group (n = 207 total) | Mean age, SD and range | Disease status | % Methanogen positive (mcrA gene) |
---|---|---|---|---|
Healthy Controls (HC) | 44 | 25.8 ± 8.3 (range 19–56) | No history of gastrointestinal illness | 48% |
Crohn's Disease (CD) | 27 | 41.3 ± 11.9 (range 25–70) | Both remission and relapse (CDAI >150 a) individuals | 30% |
Ulcerative Colitis (UC) | 29 | 49.0 ± 12.0 (range 32–70) | Both remission and relapse individuals b | 24% d |
Irritable Bowel Syndrome (IBS) | 46 | 44.4 ± 12.8 yrs, (range 24–74) | Diagnosed according to the Rome II criteria c | 48% |
Colorectal Cancer (CC) | 31 | 60.3 ± 6.6 yrs, (range 45–70) | In remission, >95% receiving a wide range of medication | 45% |
Polypectomised (PP) | 30 | 53.5 ± 9.1 yrs, (range 30–69) | Pre-cancerous polyps removed | 50% |