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Table 6 Distribution of SNPs in different gene function groups and their effects on protein sequences

From: Complete genome sequence of Treponema pallidum ssp. pallidumstrain SS14 determined with oligonucleotide arrays

Putative gene function whole genomea % affected ORFsb % SNPsc % aa changesd %
Hypothetical 316 30.4 52 38.2 199 64.2 148 67.0
Conserved hypothetical 177 17.0 21 15.4 34 11.0 22 10.0
Metabolic functions 167 16.1 19 14.1 23 7.4 19 8.6
Housekeeping genes 223 21.5 24 17.6 25 8.0 10 4.4
Other function 156 15.0 20 14.7 29 9.4 22 10.0
Total 1039 100 136 100 310 100 221 100
  1. anumber of genes (ORFs) in the complete genome of TPA Nichols strain [3]; bnumber of all genes with sequence changes in the genome of SS14 strain; cnumber of SNP changes identified within ORF groups in the genome, other sequence changes were not included; damino acid changes caused by SNPs, changes in length of the protein molecule are listed in Table 4.