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Table 5 ORFs with the highest number of detected SNPs (+ indels)

From: Complete genome sequence of Treponema pallidum ssp. pallidumstrain SS14 determined with oligonucleotide arrays

ORFa SNPs aa changes Other changes Result of mutation Protein function
TP0117 10 6    Tpr protein C (TprC)
TP0136 49 38 4 deletions (9 nt) 3 aa missing hypothetical proteinb
TP0326 12 9    outer membrane protein
TP0515 10 10    conserved hypothetical protein
TP0548 30 21 3 insertions (12 nt) 4 aa inserted hypothetical protein
TP1031 31 23    Tpr protein L (TprL)
  1. ORF – open reading frame; SNP – single nucleotide polymorphism; aa – amino acid; nt – nucleotide; aas described in [3]; bthis protein was described to be fibronectin and laminin protein [29].