Figure 4

(a) The effect of the number of inclusions on the EB yield; average RB radii of 0.5 μ m (blue), 0.55 μ m (red), 0.6 μ m (magenta), and 0.65 μ m (green). (b) Threshold curve distinguishing normal development or persistent mode of growth as predicted by the size of the RB radius and the number of inclusions. Parameter values used were: doubling time t_d = 1.8 hrs, rate of RB detachment k = 1.3 hrs^-1, EB radius r_e = 0.1 μ m, rate of RB-to-EB differentiation μ = 0.25 hrs^-1, average spacing between T3S needles on the RB surface L = 0.04 μ m, length of T3S needles l _p = 0.0078 μ m, volume of host cell Cell_Vol = 2400 μ m³, proportion of cell not available for inclusion growth ε = 0.3, and threshold number of T3S needles per RB P_lim = 23.