Figure 5
From: Characterization and partial purification of Candida albicans Secretory IL-12 Inhibitory Factor
CA-SIIF dramatically reduces CD1a expression on human monocyte-derived dendritic cells. (A) Impact of CA-SIIF on GM-CSF/IL-4 induced monocyte-derived dendritic cells. (a) CD14 expression on fresh monocytes, (b) CD1a expression on monocytes after 5 day culture with GM-CSF/IL-4 in absence of CA-SIIF, (c) CD1a expression on monocytes after 5 day culture with GM-CSF/IL-4 in presence of CA-SIIF. Flow histograms are representative of 3 independent experiments. (B) Cumulative dramatic reduction of CD1a expression on human monocytes-derived dendritic cells cultured with CA-SIIF. Cell density: 5 × 105/ml. n = 3.