Table 1 Curated list of resistance proteins

Antibiotic efflux pumps[6, 29]

PstB (Rv0933), Rv2686c, Rv2687c, Rv1688c, IniA (Rv0342), Mmr (Rv3065)

Rv3239c, Rv3728, Rv2846c, Rv1877, Rv2333c, Rv2459, Rv1410c, Rv1250, Rv1258c, Rv0783c, Rv1634, Rv0849

Hypothetical efflux pumps[29]

Rv0191, Rv0037c, Rv2456c, Rv2994

Antibiotic degrading enzymes* [6]

BlaC (Rv2068c)

Target-modifying enzymes* [30, 31]

Erm37 (Rv1988), WhiB7 (Rv3197A)

SOS and related genes[7]

DnaE2 (Rv3370c), RuvA (Rv2593c), RecA (Rv2737c), RecB (Rv0630c), RecC (Rv0631c), RecD (Rv0629c), DnaE1 (Rv1547), PolA (Rv1629), LexA (Rv2720)

Genes implicated in horizontal gene transfer[7, 32]

SecA1 (Rv3240c), SecA2 (Rv1821), Rv3659c, Rv3660c

Cytochromes[32]

CcdA (Rv0527), CcsA (Rv0529), CtaB (Rv1451), CtaC (Rv2200c), CtaD (Rv3043c), CtaE (Rv2193), CydA (Rv1623c), CydB (Rv1622c), CydC (Rv1620c), CydD (Rv1621c), Cyp121 (Rv2276), Cyp123 (Rv0766c), Cyp124 (Rv2266), Cyp125 (Rv3545c), Cyp126 (Rv0778), Cyp128 (Rv2268c), Cyp130 (Rv1256c), Cyp132 (Rv1394c), Cyp135A1 (Rv0327c), Cyp135B1 (Rv0568), Cyp136 (Rv3059), Cyp137 (Rv3685c), Cyp138 (Rv0136), Cyp139 (Rv1666c), Cyp140 (Rv1880c), Cyp141 (Rv3121), Cyp142 (Rv3518c), Cyp143 (Rv1785c), Cyp144 (Rv1777), Cyp51 (Rv0764c), DipZ (Rv2874), LldD1 (Rv0694), LldD2 (Rv1872c), QcrB (Rv2196), QcrC (Rv2194), SdhC (Rv3316)