Figure 3
From: Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance
Top scoring paths from MAP to each of the four resistance classes. Nodes are labelled by their Rv IDs, as obtained from TubercuList. Nodes correspond to the individual proteins in the network while the edges indicate interactions between them. Each class of nodes is coloured differently as indicated. Grey nodes indicate those that do not belong to any of the marked classes. The nodes are sized in proportion to the number of MAP drugs that induce its upregulation. The thickness of an edge is proportional to the number of times a shortest path is traversed through that edge. The dotted edge is not a high-scoring path but is of significance, as discussed in the text.