Microbial group in biopsy samples | Bacterial countsa (Log cells/g) | P-value Mann-Whitney/Test Bonferroni adjustment | |||||||
---|---|---|---|---|---|---|---|---|---|
 | Active CD (n = 25) | Non-active CD (n = 8) | Control (n = 8) | Active- non-active CD | Control- active CD | Control- non-active CD | |||
 | Median | IQR | Median | IQR | Median | IQR |  |  |  |
Bifidobacterium group | 5.95 | 5.55–6.21 | 6.15 | 4.97–6.28 | 6.27 | 6.03–6.80 | 0.604 | 0.009*, i | 0.461 |
B. longum | 4.66 | 4.36–5.37 | 4.95 | 4.90–5.60 | 5.60 | 5.33–5.73 | 0.310 | 0.004*, i | 0.368 |
B. breve | 5.14 | 4.59–5.46 | 3.05 | 3.02–3.50 | 5.21 | 5.00–5.80 | 0.020* | 0.630 | 0.100 |
B. bifidum | 4.35 | 3.40–4.75 | 3.98 | 2.15–4.44 | 4.17 | 3.48–4.66 | 0.800 | 0.700 | 0.950 |
B. adolescentis | 3.22 | 2.86–3.74 | 3.06 | - | 3.87 | 1.80–3.30 | 0.600 | 0.327 | 0.667 |
B. catenulatum group | 4.08 | 3.16–4.60 | 4.12 | 4.04–4.53 | 4.10 | 3.76–4.46 | 0.736 | 0.757 | 0.660 |
B. angulatum | 2.95 | 1.54–3.80 | 4.10 | - | 3.55 | 1.58–4.44 | 0.275 | 0.933 | 0.900 |
B. lactis | 6.33 | 5.50–6.18 | - | - | 5.28 | 4.59–5.70 | - | 0.033* | - |
B. longum subsp. infantis | - | - | - | - | - | - | - | - | - |
B. dentium | 4.23 | 3.45–5.23 | 4.00 | - | - | - | 0.627 | - | - |
Microbial group in faecal samples | Bacterial countsa (Log cells/g) | P-value Mann-Whitney test Bonferroni adjustment | |||||||
 | Active CD (n = 30) | Non-active CD (n = 18) | Control (n = 30) | Active- non-active CD | Control- active CD | Control- non-active CD | |||
 | Median | IQR | Median | IQR | Median | IQR |  |  |  |
Bifidobacterium group | 9.67 | 8.68–9.90 | 8.77 | 8.58–9.60 | 9.80 | 9.23–10.33 | 0.183 | 0.014*, i | 0.002*, i |
B. longum | 8.90 | 8.56–9.40 | 8.30 | 7.78–9.00 | 9.28 | 8.88–10.10 | 0.030* | 0.038* | < 0.001*, i |
B. breve | 6.97 | 5.56–7.82 | 4.02 | 3.08–5.15 | 6.94 | 6.18–8.02 | < 0.001*, i | 0.860 | < 0.001*, i |
B. bifidum | 7.64 | 6.42–8.16 | 6.74 | 6.40–6.87 | 6.96 | 6.67–7.93 | 0.030* | 0.577 | 0.050* |
B. adolescentis | 6.95 | 5.55–7.92 | 5.40 | 4.93–7.76 | 5.97 | 5.37–6.60 | 0.112 | 0.050* | 0.633 |
B. catenulatum group | 7.16 | 6.50–8.68 | 7.84 | 7.07–8.50 | 7.65 | 7.56–8.42 | 0.425 | 0.106 | 0.758 |
B. angulatum | 4.96 | 4.64–7.20 | 4.68 | 4.24–5.07 | 4.65 | 4.12–5.00 | 0.548 | 0.153 | 0.569 |
B. lactis | 7.12 | 5.30–7.45 | 5.17 | 4.66–7.20 | 5.45 | 4.66–7.07 | 0.175 | 0.081 | 0.780 |
B. longum subsp. infantis | 6.57 | 5.80–7.76 | 7.47 | 6.83–7.82 | 6.68 | 6.45–7.06 | 0.192 | 0.341 | 0.117 |
B. dentium | 6.28 | 6.10–6.30 | 5.24 | 4.66–5.82 | 5.20 | 3.86–5.30 | 0.111 | 0.133 | 0.571 |