Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease

Collado, Maria Carmen; Donat, Ester; Ribes-Koninckx, Carmen; Calabuig, Miguel; Sanz, Yolanda

doi:10.1186/1471-2180-8-232

BMC Microbiology

Table 2 Prevalence of Bifidobacterium group and species in faeces and duodenal biopsies of children

From: Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease

Microbial group in biopsy samples	Prevalence (%)^a			P-value Chi-square test Bonferroni adjustment
	Active CD (n = 25)	Non-active CD (n = 8)	Control (n = 8)	Active- non-active CD	Control- active CD	Control- non-active CD
Bifidobacterium group	100.0 (25/25)	100.0 (8/8)	100.0 (8/8)	-	-	-
B. longum	100.0 (25/25)	100.0 (8/8)	100.0 (8/8)	-	-	-
B. breve	64.0 (16/25)	37.5 (3/8)	37.5 (3/8)	0.181	0.181	0.695
B. bifidum	52.0 (13/25)	25.0 (2/8)	37.5 (3/8)	0.180	0.380	0.500
B. adolescentis	36.0 (9/25)	12.5 (1/8)	25.0 (2/8)	0.380	0.669	0.500
B. catenulatum group	52.0 (13/25)	37.5 (3/8)	87.5 (7/8)	0.381	0.050*	0.038*
B. angulatum	32.0 (8/25)	12.5 (1/8)	50.0 (4/8)	0.277	0.419	0.282
B. lactis	60.0 (15/25)	0.0 (0/8)	62.5 (5/8)	0.003*, ⁱ	0.618	0.012*, ⁱ
B. longum subsp. infantis	0.0 (0/25)	0.0 (0/8)	0.0 (0/8)	-	-	-
B. dentium	8.0 (2/25)	12.5 (1/8)	0.0 (0/8)	0.578	0.568	0.500
Microbial group in faecal samples	Prevalence (%)^a			P-value Chi-square test Bonferroni adjustment
	Active CD (n = 30)	Non-active CD (n = 18)	Control (n = 30)	Active- non-active CD	Control- active CD	Control- non-active CD
Bifidobacterium group	100.0 (30/30)	100.0 (18/18)	100.0 (30/30)	-	-	-
B. longum	100.0 (30/30)	100.0 (18/18)	100.0 (30/30)	-	-	-
B. breve	80.0 (24/30)	66.7 (12/18)	66.7 (20/30)	0.325	0.500	0.751
B. bifidum	100.0 (30/30)	100.0 (18/18)	100.0 (30/30)	-	-	-
B. adolescentis	50.0 (15/30)	83.3 (15/18)	40.0 (12/30)	0.016*, ⁱ	0.452	0.045*
B. catenulatum group	100.0 (30/30)	100.0 (18/18)	100.0 (30/30)	-	-	-
B. angulatum	20.0 (6/30)	16.7 (3/18)	23.0 (7/30)	0.546	0.601	0.521
B. lactis	56.7 (17/30)	61.1 (11/18)	63.3 (19/30)	0.502	0.975	0.775
B. longum subsp. infantis	36.7 (11/30)	22.2 (4/18)	36.7 (11/30)	0.351	0.795	0.532
B. dentium	13.3 (4/30)	27.7 (5/18)	6.6 (2/30)	0.265	0.407	0.040*

^a Prevalence (Pr) reflects the number of positive amplifications from total samples analysed by PCR (n = number of samples analysed)
* Statistical differences were calculated by using Chi-square test 2 × 2. Significantly difference between groups was consider at P < 0.050
ⁱ Statistical differences were corrected for a multiple comparison test (3 variable) by using Bonferroni adjustment. Significantly difference between groups was considered at P < 0.017.

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ISSN: 1471-2180

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