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Table 2 MBC values of H. influenzae strains

From: In vitro activity of telithromycin against Haemophilus influenzae at epithelial lining fluid concentrations

Microorganisms

Drug

Ambient air

CO2

  

Range (mg/L)

MBC50/MBC90 (mg/L)

Range (mg/L)

MBC 50 /MBC 90 (mg/L)

β-lactamase negative (n = 200)

Tel §

0.125 – 16

1/4

0.06 – 32

4/16

 

Clr

0.25 – 64

4/16

1 – 128

8/64

 

Azm

0.25 – 8

1/4

0.5 – 64

4/8

β-lactamase positive (n = 50)

Tel

0.125 – 8

1/4

0.125 – 16

4/16

 

Clr

0.5 – 32

4/16

1 – 64

8/64

 

Azm

0.25 – 8

1/4

0.5 – 32

4/8

BLNAR* (n = 10)

Tel

0.125 – 8

1/8

0.25 – 8

4/8

 

Clr

1 – 16

4/16

2 – 32

8/32

 

Azm

0.25 – 8

1/8

0.5 – 16

4/16

  1. *: BLNAR: β-lactamase negative ampicillin resistant; §: Tel: telithromycin; Clr: Clarithromycin; Azm: Azithromycin.