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Table 5 Immunoprotective effects of rOmpL1 proteins in guinea pigs

From: Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein

Group

Animals (n)

Immunizing dosage (mg/kg)

Infecting Leptospiral

Survival/Death

Protective rate

  

rOmpL1/1

rOmpL1/2

rOmpL/3

strain

(n/n)

(%)

A1

8

1.0

/

/

Lai

3/5

37.5

A2

8

2.0

/

/

Lai

5/3

62.5

A3

8

1.0

/

/

Lin 4

5/3

62.5

A4

8

2.0

/

/

Lin 4

7/1

87.5

A5

8

1.0

/

/

Pishu

2/6

25.0

A6

8

2.0

/

/

Pishu

3/5

37.5

B1

8

/

1.0

/

Lai

5/3

62.5

B2

8

/

2.0

/

Lai

6/2

75.0

B3

8

/

1.0

/

Lin 4

4/4

50.0

B4

8

/

2.0

/

Lin 4

5/3

62.5

B5

8

/

1.0

/

Pishu

2/6

25.0

B6

8

/

2.0

/

Pishu

3/5

37.5

C1

8

/

/

1.0

Lai

2/6

25.0

C2

8

/

/

2.0

Lai

3/5

37.5

C3

8

/

/

1.0

Lin 4

3/5

37.5

C4

8

/

/

2.0

Lin 4

4/4

50.0

C5

8

/

/

1.0

Pishu

5/3

62.5

C6

8

/

/

2.0

Pishu

6/2

75.0

D1

8

/

/

/

Lai

0/8

/

D2

8

/

/

/

Lin 4

0/8

/

D3

8

/

/

/

Pishu

0/8

/