Evaluation of an in silico predicted specific and immunogenic antigen from the OmcB protein for the serodiagnosis of Chlamydia trachomatis infections

Table 5 Performance of the OmcB Ct ELISA in selected populations.

Reference test	Population	No. of sera	ELISA+/ELISA-	Specificity (%)	Sensitivity (%)
MIF	Children MIF CT-CP-	52	3/49	94.2 (49/52)	NA
	Adulte MIF CT-CP+	52	3/49	94.2 (49/52)	NA
	Patients MIF CT+CP-	24	1/24	NA	4.7 (1/24)
PCR	Patients PCR CT-	30	2/28	93.3 (28/30)	NA
	Patients PCR CT+	14	4/14	NA	28.6 (4/14)

NA: not applicable, ELISA positivity: OD ≥ 0.764. Children MIF CT-CP-: children sera MIF C. trachomatis negative C. pneumoniae negative, patients MIF CT-CP+: patients MIF C. trachomatis negative C. pneumoniae positive, patients MIF CT+CP-: patients MIF C. trachomatis positive C. pneumoniae negative, Patients PCR CT-: patients that are C. trachomatis PCR negative, Patients PCR CT+: patients that are C. trachomatis PCR positive.

ISSN: 1471-2180