Comparison of the tc -PAIYein Yersiniae. Three homology groups are depicted, namely tcaAB/tcdA, tcaC/tcdB, and tccC. tcdA/tcdB homologous are present only in Y. enterocolitica strain T83. tcaR1 (left) encoding a regulator and tldD encoding a putative DNA gyrase modulator (right, checkered) mark the island insertion site common for all Yersinia strains that harbour tc homologues. Identically coloured arrows mark homologous genes. A transposase-like gene (tnp) is present in the genome of Y. pestis Angola (black arrow). The overall gene organisation is similar for all strains harbouring insecticidal determinants, but differences with respect to gene homology, hypothetical ORFs, the presence of transposase-like elements and the number of tccC genes are also visible. Gene lengths and intergenic regions are in scale. Asterisks mark frameshifts. With the exception of tcaC, all frameshifts result in two ORFs. Y. ptb., Y. pseudotuberculosis.