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Table 1 Analytical sensitivity of Candida cells capture with IMS method

From: Evaluation of an immunomagnetic separation method to capture Candida yeasts cells in blood

Strains Time (hours) of positive blood culture
(mean ± SD)a
CFU/ml in initial contaminated blood CFU/ml after IMS
(mean ± SD)a
Immunocaptured cells
(% ± SD)ab
Candida albicans 5575 25.45 ± 0.59 32 8.8 ± 0.6 27.5 ± 1.9
Candida albicans ATCC 66396 25.95 ± 1.46 6 1.75 ± 0.3 29.1 ± 3.8
Candida krusei 5374 22.26 ± 0.48 30 3.25 ± 0.5 10.8 ± 1.7
Candida krusei 5481 16.20 ± 0.28 40 17.3 ± 2.5 43.2 ± 6.2
Candida glabrata 5511 25.05 ± 0.5 20 7.6 ± 1.3 38 ± 6.4
Candida glabrata 5484 25.38 ± 0.58 10 3.8 ± 0.6 38 ± 6.3
Candida tropicalis 5437 19.02 ± 0.88 30 4.8 ± 2.2 16 ± 3.8
Candida tropicalis 5395 17.51 ± 0.50 30 4.3 ± 2.2 14.3 ± 7.3
  1. acalculation of mean and SD is derived from three different experiments
  2. bpercentage of immunocaptured cells: number of CFU per 1 ml of blood after IMS procedure/number of CFU per 1 ml of blood in initial contaminated blood
  3. CFU: Colony Forming Unit, IMS : ImmunoMagnetic Separation, SD : Standard Deviation