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Table 3 Informative powers of SNP sets.

From: Assignment of Streptococcus agalactiae isolates to clonal complexes using a small set of single nucleotide polymorphisms

Generally applicable SNP profile CCGG1as a diagnostic for CC17.

Calculated against all STs

Sensitivity = 0.91

Specificity = 0.98

PPV = 0.90

Safety net SNP atr351 "A" allele of as a diagnostic for CC17 – calculated against subsets of STs defined by generally applicable SNPs

CC67 profile STs

Sensitivity = 1

Specificity = 0.13

PPV = 0.07

CC23 profile STs

Sensitivity = 1

Specificity = 0.79

PPV = 0.14

CC17 profile STs

Sensitivity = 1

Specificity = 1

PPV = 1

Safety net SNP "A" allele as a diagnostic for CC17

Calculated against all STs

Sensitivity = 0.92

Specificity = 0.82

PPV = 0.45

Safety net SNP "A" allele as a diagnostic for CC17, CC67, CC22 eBURST group

Calculated against all STs

Sensitivity = 0.94

Specificity = 0.95

PPV = 0.85

  1. 1. The generally applicable SNP profile consists of alleles at glnA36, glnA429, glcK180, and adhP111; the safety net SNP is atr351