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Table 1 S. Typhimurium mutants that exhibited different type 1 fimbrial phenotypes than the parental strain

From: Identification of the genetic determinants of Salmonella enterica serotype Typhimurium that may regulate the expression of the type 1 fimbriae in response to solid agar and static broth culture conditions

Category Mutant Phenotype Genea Function
   (agar, broth)   
Fimbrial biosynthesis and regulation K2 -, - fimZ Positive regulator of type 1 fimbriae major subunit gene fimA
  K14 -, - fimY Positive regulator of type 1 fimbriae major subunit gene fimA
  K40 -, - fimA Major subunit of type 1 fimbriae
  K66 -, - fimD Fimbrial usher protein of FimA
  K75 -, - fimC Fimbrial chaperone protein of FimA
  K44 -, - fimH Adhesin of type 1 fimbriae
  K70 +, + lpfB Fimbrial chaperone protein of long polar fimbriae
  K61 +, + pefI Regulator of plasmid-encoded fimbriae
  K23 +, + stbC Fimbrial usher protein of Stb fimbriae
Putative cytoplasmic protein K1 +, + STM1078 Putative cytoplasmic protein
  K28 +, + STM4529 Putative cytoplasmic protein
Global regulator K46 -, - lrp Leucine-responsive regulatory protein
  K15 -, - hupA Histone-like DNA binding protein
Membrane associated protein K17, +, + yhjV Putative transporter protein
  K39 -, - STM1128 Putative sodium/glucose cotransporter
  K45 -, - yihO Putative glycoside-pentoside-hexuronide (GPH) family transport protein
  K50 +, + STM2532 Putative inner membrane lipoprotein
  K52 +, + STM2486 Putative inner membrane protein
  K54 -, - yjiH Putative inner membrane protein
  K72 +, + mgtB Mg2+ transporter protein
  K30 +, + narK Nitrate/nitrite transporter protein
Cell envelope associated protein K60 +, + ytfB Putative cell envelope opacity-associated protein A
Periplasmic protein K69 +, + ydbH Putative periplasmic protein
Ribosome modulation factor K56 -, - rmf Ribosome modulation factor
Type III secretion system K55 -, - ssaB Effector protein of type III secretion system
  K59 +, + invB Chaperone protein for SopE/SopE2
  K63 -, - ssaV Apparatus protein for intracellular trafficking and secretion
Prophage-derived protein K11 +, + STM4200 Putative phage tail protein H
  K33 +, + sseI Gifsy-2 prophage putative type III secreted effector protein
  K19 -, - STM1041 Gifsy-2 prophage probable minor tail protein
Sensor protein K51 +, + ssrA Sensor component of type III secretion system
  K58 +, + yehU Sensor component
Transcription termination factor K73 -, - nusA Transcription termination factor
Enzymes K3 -, - cafA Endoribonuclease
  K5 +, + res Subunit of type III restriction-modification enzyme
  K8 +, + STM4467 Putative arginine deiminase
  K16 +, + STM1627 Alcohol dehydrogenase class III
  K31 +, + STM2446 Putative iron-dependent peroxidase
  K41 -, - nuoE NADH dehydrogenase I chain E
  K37 +, + yafA Putative hydrolase
  K43 -, - miaA Isopentenylpyrophosphate transferase
  K38 -, - prC C-terminal protease for penicillin binding protein
  K47 -, - atpH Membrane-bound ATP synthase
  K48 +, + ubiB NAD(P)H-flavin reductase
  K49 -, - ydiF Putative acetyl-CoA: acetoacetyl-CoA transferase
  K53 +, + tdK Thymidine kinase
  K65 +, + pps Phosphoenolpyruvate synthase
  K57 +, + ybjX Putative enzyme with unknown function
  K67 +, + pncA Nicotinamidase/pyrazinamidase
  K68 +, + rfaB Lipopolysaccharide 1,6-galactosyltransferase
  K71 +, + xapB Xanthosine permease
  K64 +, + STM1940 Putative cell wall-associated hydrolase
  K74 +, + cbiA Cobyrinic acid a, c-diamide synthase
  K42 -, - aroA 3-enolpyruvylshikimate-5-phosphate synthetase
  1. a: The gene that was disrupted by the transposon insertion is listed. The annotation of S. Typhimurium LT2 genome is used if the transposon insertion was present in a gene which is uncharacterized and unnamed.