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Figure 2 | BMC Microbiology

Figure 2

From: Natriuretic peptides modify Pseudomonas fluorescens cytotoxicity by regulating cyclic nucleotides and modifying LPS structure

Figure 2

Effect of brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP) (10-6 M) on the necrotic activity of Pseudomonas fluorescens MF37. The necrotic effect of the bacterium was determined by measurement of the accumulation in the medium of lactate dehydrogenase (LDH) resulting from rupture of the cytoplasmic membrane of glial cells and consequently release of the enzyme. Values are expressed as the mean concentration of LDH in the culture medium after 24 h of incubation with untreated (n = 20) or treated (n = 20 for BNP, and n = 17 for CNP) bacteria. Data are means for four independent experiments. * : Significantly different (P < 0.05). *** : Significantly different (P < 0.001).

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