Skip to main content

Advertisement

Table 1 Demographic, serological and molecular data of the patients

From: Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil

Patient Sex Age HIV Lamivudine treatment (months) HBe/AntiHBe HBV load (copies/mL) Phenotypic resistance Lamivudine resistance mutations (rt)
HBV DNA negative
16-ufmt F 69 No 16 HBeAg <102 No -
10-ufmt F 60 No 14 Anti-HBe <102 No -
35-ufmt M 58 No 50 Anti-HBe <102 No -
12-ufmt M 44 No 24 Anti-HBe <102 No -
Genotype A1
05-hac M 58 No 34 nd 8 × 104 Yes M204I
01-hgg M 56 Yes 60 HBeAg 8 × 106 Yes L180M/M204V
02-hgg M 50 Yes 84 Anti-HBe 1 × 106 Yes L180M/M204V
04-hgg M 43 Yes 32 HBeAg 7 × 106 Yes L180M/M204V
06-hgg M 34 Yes 72 HBeAg 1 × 107 Yes L180M/M204V
07-hgg M 61 Yes 32 HBeAg 1 × 108 Yes L180M/M204V
10-hgg M 46 Yes 42 HBeAg 4 × 105 Yes L180M/M204V
11-hgg M 40 Yes 30 HBeAg 1 × 107 Yes L180M/M204I
30-ufmt M 47 Yes 33 HBeAg 2 × 108 Yes L180M/M204V
34-ufmt M 12 Yes 24 Anti-HBe 3 × 106 Yes L180M/M204V
03-hgg M 35 Yes 72 HBeAg 9 × 105 Yes V173L/L180M/M204V
08-hgg M 60 Yes 31 HBeAg 1 × 106 Yes V173L/L180M/M204V
03-hac F 55 No 14 HBeAg nd Yes No
04-hac M 60 No 71 nd nd No No
05-ufmt M 47 No 47 nd 3 × 106 No No
09-ufmt F 21 No 21 HBeAg nd No No
20-ufmt M 28 No 13 Anti-HBe 7 × 105 No No
26-ufmt M 56 No 26 Anti-HBe 6 × 106 Yes No
27-ufmt M 53 No 30 HBeAg 4 × 108 No No
29-ufmt M 37 No 23 Anti-HBe 3 × 106 No No
Genotype A2
02-hac F 54 No 44 HBeAg nd Yes L180M/M204V
32-ufmt M 53 No 59 HBeAg 3 × 107 Yes L180M/M204V
42-ufmt M 33 No 48 Anti-HBe 1 × 108 Yes L180M/M204V
41-ufmt M 76 No 34 Anti-HBe 1 × 106 No No
Genotype C
23-ufmt F 25 No 51 HBeAg 2 × 107 Yes L180M/M204V
Genotype D
39-ufmt F 25 No 12 nd 4 × 107 Yes No
13-ufmt M 68 No 40 HBeAg nd No No
07-hac M 57 No 36 Anti-HBe 1 × 108 Yes No
Genotype F
01-ufmt M 38 No 64 Anti-HBe 2 × 106 Yes L180M/M204I
Genotype G
05-hgg M 55 Yes 48 HBeAg/AntiHBe 5 × 106 Yes L180M/M204V
06-hac M 46 No 51 Anti-HBe 3 × 106 Yes L180M/M204V
09-hgg M 42 Yes 44 HBeAg 6 × 106 Yes L180M/M204V
  1. nd, not determined