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Figure 11 | BMC Microbiology

Figure 11

From: Automated discovery and phylogenetic analysis of new toxin-antitoxin systems

Figure 11

(a) Schematic of the "ancestral sequence tree" method used for inferring the phylogeny among putative toxins sequences uncovered by TAQ V1.0. In this hypothetical example, the sequences are separated into 4 groups. Black edges represent the ML phylogenies within each of the 4 considered groups. The red dots stand for the inferred ancestral sequence of each group. The red edges define the phylogeny among the inferred ancestral sequences. (b) Schematic of the second heuristic ("super tree" approach) used for inferring the phylogeny among putative toxins sequences uncovered by TAQ V1.0. In this hypothetical example, the sequences are separated into 3 groups. The red, green, and blue trees represent the ML phylogenies within each of the 3 considered groups. These source trees are then used collectively for generating the best super tree, i.e., the tree including all sequences that is most compatible with all source trees (see Methods section for details).

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