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Figure 4 | BMC Microbiology

Figure 4

From: Cirrhosis-induced defects in innate pulmonary defenses against Streptococcus pneumoniae

Figure 4

Quantification of complement deposition on pneumococci recovered from the lungs of cirrhotic and control rats 15 min after infection with 1 × 109 cfu of S. pneumoniae ATCC 6303. Flow cytometry was used to determine: (A) – percentage of pneumococci positive for bound C3; (B) – mean fluorescent intensity of pneumococci with bound C3; and (C) – deposition index calculated by multiplying the percentage of pneumococci positive for C3 by their fluorescent intensity. Both the mean fluorescent intensity (*: p = 0.04) and deposition index (**: p = 0.01) were significantly lower for organisms recovered from the lungs of cirrhotic vs. control rats.

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