Figure 6

Examples of lung pathology post B. pertussis inoculation. Lung sections (H&E, obj x 20) from B. pertussis infected mice. A: HcB28 day 1, mild alveolitis (grade 2 on scale from 1–5), as seen by inflammatory cells in alveolar septa and spaces. B: C3H day 3, alveolitis and thickened septa (pneumonia) varying from grade 3 (upper, right) to 5 (bottom). C: C3H day 3, asterix: perivasculitis grade 5, and arrow: hypertrophy bronchiolar epithelium, grade 3. D: HcB28 day 3, no major differences in pathology compared to C3H (B and C).