Figure 4

Bacteria titers in the blood of mice challenged with isogenic mutants of RD8. Mice were challenged with 10⁷ cfu of TIGR4 and isogenic mutants deficient in operons within RD8. Two days post-challenge, blood was collected from the tail vein and the number of bacteria in the blood determined. Each circle represents the bacterial titer of an individual mouse. Bars indicate the median bacterial titer. Statistical analysis was performed using a Mann Whitney Rank Sum Test