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Figure 1 | BMC Microbiology

Figure 1

From: HCMV-infection in a human arterial organ culture model: effects on cell proliferation and neointimal hyperplasia

Figure 1

Human organ cultures with double stainings against HCMV-antigens and von Willebrand factor (identification of endothelial cells) or smooth muscle α-actin (identification of smooth muscle cells). The endotheliotropic character of TB40E is demonstrated by the presence of HCMV early antigen after 3, 14, and 21 days (big arrow; A, B, C) within von Willebrand positive cells (small arrow); no smooth muscle α-actin positive cells are found in the area of the TB40E-virus (day 14; B). The tropism of AD169 as fibroblast adapted strain to smooth muscle cells is demonstrated by the presence of HCMV early antigen (big arrow; D, E, F) within α-actin positive cells (small arrow); no positive stainings against von Willebrand factor are found in the area of the AD169-virus (day 7; D).

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BMC Microbiology

ISSN: 1471-2180

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