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Table 1 Scoring system to quantify Haemophilus influenza [NTHi] pathogenicity in the CGS-chinchilla model.

From: Virulence phenotypes of low-passage clinical isolates of Nontypeable Haemophilus influenzae assessed using the chinchilla laniger model of otitis media

Otologic Score 0 1 2 3 4  
Degree of otoscopic changes (inflammation) None Mild Moderate Frank purulence Tympanic membrane rupture  
Systemic Score 0 0.5 1 2 3 4
Systemic description normal Slightly lethargic Upright and steady on feet Immediately responds to stimulation by actively moving around cage Eating and drinking Slightly lethargic Upright and steady on feet Head and ears down Responds by actively moving around cage rapidly when stimulated by voice or touch Eating and drinking Eyes 1/2 open Moderately lethargic Slightly ataxic Able to keep self upright Moving around cage slowly only when stimulated by voice or touch Eating treats and drinking water Same as 2 but not eating or drinking Supportive treatment given (fluids and Buprenex) Extremely lethargic Extremely ataxic Not able to maintain an upright position Barely moving around cage Dyspnea Sacrificed