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Table 2 Sequence differences in base pairs (bp) by isolate and amplified fragment

From: Helicobacter pylori genome variability in a framework of familial transmission

Isolate Sequence differences by PCR fragment (length of sequence in bp)
(RAPD type) hsdS (571/607)1 cag2 (330/475)2 flab (487) mutY (439) ureI (576)
15:7 (A) 01 02 273 194 0
15:8 (A) 01 02 273 194 0
15:10 (A) 01 02 273 194 0
16:1 (B) 0 0 0 0 65
16:3 (B) 0 0 0 0 0
16:13 (B) 0 0 0 0 15
13:5 (B) 0 0 0 134 0
13:10 (B) 0 0 0 134 0
13:11 (B) 0 0 0 134 0
125:3 (B) 0 0 0 0 0
125:7 (B) 0 0 0 0 0
125:11 (B) 0 0 0 0 0
24a:5 (B) 0 0 0 0 0
24a:10 (B) 0 0 0 0 0
24a:12 (B) 0 0 0 0 0
  1. Sequence differences were assessed between 15 H. pylori isolates, three isolates from each of biopsy 15 and 16 from the mother and of biopsy 13, 125 and 24a from the three children.
  2. 1The 571 bp fragments from isolates from biopsy 15 differed significantly from the 607 bp fragments from the other isolates and were aligned separately.
  3. 2The 330 bp cag2 (HP0521) fragments were obtained from isolates from biopsy 15, while 475 bp fragments of the HP0521B gene were amplified from the other isolates, and separate alignments were performed.
  4. 3Sequences are identical within biopsy 15.
  5. 4Sequences are identical within biopsy 15 and 13, respectively, and the difference of 13 bp is shared between isolates from biopsy 15 and 13.
  6. 5The difference of 1 bp is not shared between isolates 16:1 and 16:13