Widespread pyocyanin over-production among isolates of a cystic fibrosis epidemic strain

BMC Microbiology

Table 3 LES lasR mutants

LES isolate	lasR Mutation	Comments/Reference
LESB41	deletion of CCGGGCTGGCTACG leading to divergence from position R₆₆ onward	isolated from patient C
LESB30	single point mutation leading to divergence from position S₃₃ onward	isolated from patient F
LESB32	single nucleotide insertion/frame-shift mutation leading to divergence from position L₂₂₃ onward	isolated from patient A
LESB25	same as LESB32	isolated from patient A
LES49111	same as LESB32	isolated from patient A
LES49074	same as LESB32	isolated from patient A
LESB63	same as LESB32	isolated from patient D
LESB62	single point mutation leading to single amino acid change H₂₂₄ → R	isolated from patient D
LESB4	same as LESB32	isolated from patient E
LESB51	same as LESB32	isolated from patient E
LESB67	deletion of AAGCGGAA leading to divergence from position A₁₃₄ onward	isolated from patient E
LES49220	single point mutation leading to single amino acid change G₂₃₅ → D	CF isolate, isolated in 2004
LES400	repetition of GGTGCTC leading to divergence from G₁₂₃ onward	[17]
LES430	deletion of GTGGATGCTC leading to divergence from position W₁₅₂ onwards	[17]
LESB44	insertion of GAAG leading to divergence from position I₃₅ onwards	[17]

ISSN: 1471-2180