TY - JOUR AU - Fagerlund, Annette AU - Brillard, Julien AU - Fürst, Rainer AU - Guinebretière, Marie-Hélène AU - Granum, Per Einar PY - 2007 DA - 2007/05/21 TI - Toxin production in a rare and genetically remote cluster of strains of the Bacillus cereus group JO - BMC Microbiology SP - 43 VL - 7 IS - 1 AB - Three enterotoxins are implicated in diarrhoeal food poisoning due to Bacillus cereus: Haemolysin BL (Hbl), Non-haemolytic enterotoxin (Nhe), and Cytotoxin K (CytK). Toxin gene profiling and assays for detection of toxin-producing stains have been used in attempts to evaluate the enterotoxic potential of B. cereus group strains. B. cereus strain NVH 391/98, isolated from a case of fatal enteritis, was genetically remote from other B. cereus group strains. This strain lacked the genes encoding Hbl and Nhe, but contains CytK-1. The high virulence of this strain is thought to be due to the greater cytotoxic activity of CytK-1 compared to CytK-2, and to a high level of cytK expression. To date, only three strains containing cytK-1 have been identified; B. cereus strains NVH 391/98, NVH 883/00, and INRA AF2. SN - 1471-2180 UR - https://doi.org/10.1186/1471-2180-7-43 DO - 10.1186/1471-2180-7-43 ID - Fagerlund2007 ER -