Characterisation of the genetic diversity of Brucella by multilocus sequencing

BMC Microbiology

Table 5 Multilocus linkage disequilibrium analysis of the 160 Brucella isolates examined.

Group (n)	V_e^a	V_o^a	sI_A^b	P ^b
Total isolates (160)	2.022	5.719	0.2286	0.001
Total STs (27)	1.825	4.679	0.1954	0.001
B. abortus (21)	0.958	2.913	0.2549	0.001
B. abortus STs (6)	1.564	5.067	0.2798	0.007
B. melitensis (21)	0.799	1.302	0.0787	0.001
B. melitensis STs (6)	0.924	0.695	-0.0310	0.808
B. suis (50)	1.154	3.646	0.2699	0.001
B. suis STs (6)	1.164	1.981	0.0876	0.054
Marine mammal (46)	1.257	3.171	0.1903	0.001
Marine mammal STs (5)	1.380	1.333	-0.0042	0.557

^a V_eis the expected variance if the alleles present at different loci in a strain are independent (i.e. no linkage disequilibrium), V_o is the observed variance.
^b Standardised I_A [26] calculated using LIAN3.1. P = probability of observing a V_o/V_e ratio equal or more extreme to that found in the original data based on 1,000 Monte Carlo randomisations.

ISSN: 1471-2180