From: Assessing the reliability of eBURST using simulated populations with known ancestry
Simple tests for populations in which eBURST is likely to be unreliable |
---|
1) Display population snapshot – is there a single large straggly group? |
2) Display undrawn SLV links – are there long range SLV links across this group? |
3) Calculate proportion of STs in the largest group – is it greater than 25%? |
If the answer to all three questions is yes, then there is probably a high rate of recombination compared to mutation and the performance of eBURST will be poor. |