Table 1 Putative DNA repair genes of C. crescentus for Base Excision Repair
From: Genome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus
| Â | Genes in E. coli(protein size) | Description | Orthologs in C. crescentus | Similarity with E. colia |
|---|---|---|---|---|
Monofunctional DNA glycosylases | alkA (282 aa) | 3-methyl-adenine DNA glycosylase II, inducible enzyme | CC2201 | 74/168 (44%) |
| Â | mutY (350 aa) | adenine glycosylase | CC0377 | 178/350 (50%) |
| Â | tag (187 aa) | 3-methyl-adenine DNA glycosylase I, constitutive enzyme | CC0382 | 116/179 (64%) |
| Â | ung or udg (229 aa) | uracil-DNA-glycosylase | 1-CC2084; 2-CC1333; 3-CC2333; 4-CC1549; | no similarity |
Bifunctional DNA glycosylases | fpg (mutM) (269 aa) | formamidopyrimidine DNA glycosylase | CC3707 | 150/286 (52%) |
| Â | nei (263 aa) | endonuclease VIII and DNA N-glycosylase with an AP lyase activity | absent | Â |
| Â | nth (211 aa) | endonuclease III; specific for apurinic and/or apyrimidinic sites | 1-CC3731; 2-CC2272 | 136/204 (66%) 77/190 (40%) |
AP endonucleases | nfo (285 aa) | endonuclease IV | absent | Â |
| Â | nfi (223 aa) | endonuclease V | absent | Â |
| Â | xthA (268 aa) | exodeoxyribonuclease III | 1-CC3706 2-CC2011; | 140/282 (49%) 138/274 (50%) |