Figure 2From: Identification and regulation of expression of a gene encoding a filamentous hemagglutinin-related protein in Bordetella holmesiiSchematic representation of the overall structureof FHA proteins of B. pertussis and B. holmesii. Protein regions with known or presumable functional importance are represented by dark grey boxes. The arrow indicates the maturation site for proteolytic cleavage of the B. pertussis FHA by the SphB1 protease. Abbreviations: N, N terminus; C, C terminus; SP, signal peptide; TPS, two-partner secretion domain; HBD, heparin binding domain; RGD, arginine-glycine-aspartic acid motif; CRD, carbohydrate binding motif; KGD, lysine-glycine-aspartic acid motif. Numbers indicate amino acid positions within the FHA proteins.Back to article page