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Figure 6 | BMC Microbiology

Figure 6

From: Structure-based discovery of inhibitors of the YycG histidine kinase: New chemical leads to combat Staphylococcus epidermidis infections

Figure 6

Binding affinities of the potential YycG inhibitors to the YycG' protein determined by using SPR. Real-time measurement of the interactions of compounds 1 (A) and 7 (B) to the YycG' protein was done by using the Biacore 3000 instrument. The curves represented the interaction of various concentrations of compounds (shown in the figures) with the protein. The compounds were injected for 120 s, and dissociation was monitored for more than 150s (see Methods).

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