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Table 2 Description of the M. tuberculosis clusters found in Venezuela.

From: Molecular characterisation of Mycobacterium tuberculosis isolates in the First National Survey of Anti-tuberculosis Drug Resistance from Venezuela

1SIT

Spoligotyping patterns -Binary description

2n

%

3Clade

4C-1

17

122

21.94

LAM-2

Ubiquitous

42

86

15.47

LAM-9

Ubiquitous

93

70

12.59

LAM-5

Ubiquitous

53

26

4.6S

T-1

Ubiquitous

20

26

4.63

LAM-1

Ubiquitous

605

18

3.24

U

Loc (VEN/USA)

1691

14

2.52

LAM-2

Endemic (VEN)

60

13

2.39

LAM-4

Ubiquitous

905

10

1.60

U

Loc (VEN-USA-ARG)

118

9

1.61

T-2

Ubiquitous

50

9

1.61

H-3

Ubiquitous

51

8

1.43

T-1

Ubiquitous

333

7

1.25

LAM-5

Loc (GUP-GUF-HTI-VEN)

960

5

0.90

U

Loc (VEN-USA)

34

5

0.90

S

Ubiquitous

194

5

0.90

LAM-4

Loc (USA-BRA-MEX-VEN)

1696

5

0.90

LAM-5

Endemic (VEN)

47

5

0.90

H-1

Ubiquitous

130

4

0.71

LAM-3

Ubiquitous

150

4

0.71

LAM-9

Ubiquitous

397

4

0.71

U

Loc (ITA-BRA-ARG-USA-VEN)

1692

4

0.71

U

Endemic (VEN)

1700

4

0.71

T-1

Endemic (VEN)

33

3

0.54

LAM-3

Ubiquitous

44

3

0.54

T-4

Ubiquitous

58

3

0.54

T-5

Ubiquitous

64

3

0.54

LAM-6

Ubiquitous

162

3

0.54

U

Loc (ARG-VEN-USA-FIN-FXX-ITA)

376

3

0.54

LAM-3

Loc (VEN-USA)

578

3

0.54

LAM-9

Loc (USA-VEN)

1698

3

0.54

U

Endemic (VEN)

1701

3

0.54

LAM-9

Endemic (VEN)

1702

3

0.54

LAM-5

Endemic (VEN)

1705

3

0.54

T-1

Endemic (VEN)

1713

3

0.54

LAM-1

Endemic (VEN)

1718

3

0.54

LAM-9

Endemic (VEN)

52

2

0.36

T-2

Ubiquitous

62

2

0.36

H-1

Ubiquitous

71

2

0.36

S

Ubiquitous

106

2

0.36

U

Loc (CUB-ECU-M EX-USA-VEN)

132

2

0.36

U

Loc (ESP-AUS-BRA-VEN)

167

2

0.36

T

Ubiquitous

178

2

0.36

LAM-4

Loc (CUB-SEN-VEN)

196

2

0.36

T-1

Ubiquitous

388

2

0.36

LAM-9

Ubiquitous

389

2

0.36

LAM-1

Loc (BRA-PRT-FIN-VEN)

430

2

0.36

T-4

Loc (USA-VEN)

1166

2

0.36

T-1

Ubiquitous (MWI-USA-VEN)

1661

2

0.36

LAM-2

Loc (VEN-BRA)

1693

2

0.36

LAM-5

Endemic (VEN)

1699

2

0.36

LAM-9

Endemic (VEN)

1703

2

0.36

LAM-9

Endemic (VEN)

1704

2

0.36

LAM-5

Endemic (VEN)

1707

2

0.36

T-1

Endemic (VEN)

1711

2

0.36

LAM-2

Endemic (VEN)

1714

2

0.36

LAM-9

Endemic (VEN)

1715

2

0.36

LAM-4

Endemic (VEN)

1716

2

0.36

T-3

Endemic (VEN)

1719

2

0.36

LAM-2

Endemic (VEN)

1694

1

0.18

LAM-5

Loc (VEN-USA)-Cluster inter-region

1695

1

0.18

LAM-2

Loc (VEN-BRA)-Cluster inter-region

1697

1

0.18

LAM-9

Loc (VEN-FXX)-Cluster inter-region

1706

1

0.18

LAM-9

Loc (VEN-USA)-Cluster inter-region

1708

1

0.18

LAM-9

Loc (VEN-LVA)-Cluster inter-region

1709

1

0.18

LAM-5

Loc (VEN-USA)-Cluster inter-region

1710

1

0.18

LAM-4

Loc (VEN-NLD)-CIuster inter-region

1717

1

0.18

X-1

Loc (VEN-AUS)-Cluster inter-region

Total

 

556

100

  
  1. 1SIT, designation of the spoligotype in the international database [19]. 2n: Number of strains. 3Clade: defined mainly as described [20, 21] LAM: Latin American and Mediterranean, H: Haarlem, T (ill-defined T clade), S: S clade, X: X clade, U: Undesignated. 4C-1: qualifier that tentatively defines an SIT as Endemic, Loc: localized or ubiquitous, as defined in Filliol et al. [20]. Geographic distribution: VEN: Venezuela, USA: United States of America, BRA: Brazil, GUP: Guadeloupe, GUF: French Guiana, HTI: Haiti, ESP: Spain, ECU: Ecuador, ARG: Argentina, CUB: Cuba, MEX: Mexico, SEN: Senegal, PRT: Portugal, FIN: Finland, ITA: Italy, MWI: Malawi, FXX: Metropolitan France, LVA: Latvia, NLD: The Netherlands, AUS: Australia.