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Table 1 Prevalence of M. tuberculosis drug resistance in Venezuela, 1998–1999.

From: Molecular characterisation of Mycobacterium tuberculosis isolates in the First National Survey of Anti-tuberculosis Drug Resistance from Venezuela

  Never treated
n(%)
Previously treated cases
n(%)
Total
n(%)
Total number of cultures 769 (88) 104 (12) 873(100)
Susceptible to all drugs 711(92.5) 72 (69.2) 783(90)
Resistant to one or more drugs 58 (7.5) 32(30.8) 90(10.3)
Resistant to only one drug 38(4.9) 12(1.5) 50(5.7)
H 13(1.7) 6(5.8) 19(2.1)
R 3(0.4) 3(2.9) 6(0.6)
E 1(0.1) 0(0.0) 1(0.1)
S 21(2.7) 3(2.9) 24(2.7)
MDR (Multidrug resistance) 4(0.5) 14(13.5) 18(2.1)
H+R 2(0.3) 4(3.8) 6(0.7)
H+R+S 1(0.1) 5(4.8) 6(0.6)
H+R+E 0(0.0) 2(1.9) 2(0.2)
H+R+E+S 1(0.1) 3(2.9) 4(0.4)
Other patherns 16(2.1) 6(5.8) 22(2.5)
H+E 2(0.3) 1(1.0) 3(0.3)
H+S 10(1.3) 3(2.9) 13(1.5)
E+S 2(0.3) 0(0.0) 2(0.2)
R+E 1(0.1) 0(0.0) 1(0.1)
H+E+S 1(0.1) 0(0.0) 1(0.1)
R+E+S 0(0.0) 2(1.9) 2(0.2)
  1. Never treated patients
  2. Total H resistance: 30/769 × 100 = 4%
  3. Total R resistance: 8/769 × 100 = 1%
  4. Total E resistance: 8/769 × 100 = 0.9%
  5. Total S resistance: 36/769 × 100 = 0.7%
  6. Total MDR resistance: 4/769 × 100 = 0.5%
  7. Previously treated patients
  8. Total H resistance: 24/104 = 23%
  9. Total R resistance: 19/104 = 18.3%
  10. Total E resistance: 8/104 × 100 = 7.7%
  11. Total S resistance: 16/104 × 100 = 15.3%
  12. Total MDR resistance: 14/104 = 13.5%
  13. Results of the first survey of anti-tuberculosis drug resistance in Venezuela during 1998–1999.
  14. Resistance to drugs: Isoniazid (H), Rifampicin (R), Ethambutol (E), Streptomycin (S) in never treated and previously treated patients.