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Table 1 Prevalence of M. tuberculosis drug resistance in Venezuela, 1998–1999.

From: Molecular characterisation of Mycobacterium tuberculosis isolates in the First National Survey of Anti-tuberculosis Drug Resistance from Venezuela

 

Never treated

n(%)

Previously treated cases

n(%)

Total

n(%)

Total number of cultures

769 (88)

104 (12)

873(100)

Susceptible to all drugs

711(92.5)

72 (69.2)

783(90)

Resistant to one or more drugs

58 (7.5)

32(30.8)

90(10.3)

Resistant to only one drug

38(4.9)

12(1.5)

50(5.7)

H

13(1.7)

6(5.8)

19(2.1)

R

3(0.4)

3(2.9)

6(0.6)

E

1(0.1)

0(0.0)

1(0.1)

S

21(2.7)

3(2.9)

24(2.7)

MDR (Multidrug resistance)

4(0.5)

14(13.5)

18(2.1)

H+R

2(0.3)

4(3.8)

6(0.7)

H+R+S

1(0.1)

5(4.8)

6(0.6)

H+R+E

0(0.0)

2(1.9)

2(0.2)

H+R+E+S

1(0.1)

3(2.9)

4(0.4)

Other patherns

16(2.1)

6(5.8)

22(2.5)

H+E

2(0.3)

1(1.0)

3(0.3)

H+S

10(1.3)

3(2.9)

13(1.5)

E+S

2(0.3)

0(0.0)

2(0.2)

R+E

1(0.1)

0(0.0)

1(0.1)

H+E+S

1(0.1)

0(0.0)

1(0.1)

R+E+S

0(0.0)

2(1.9)

2(0.2)

  1. Never treated patients
  2. Total H resistance: 30/769 × 100 = 4%
  3. Total R resistance: 8/769 × 100 = 1%
  4. Total E resistance: 8/769 × 100 = 0.9%
  5. Total S resistance: 36/769 × 100 = 0.7%
  6. Total MDR resistance: 4/769 × 100 = 0.5%
  7. Previously treated patients
  8. Total H resistance: 24/104 = 23%
  9. Total R resistance: 19/104 = 18.3%
  10. Total E resistance: 8/104 × 100 = 7.7%
  11. Total S resistance: 16/104 × 100 = 15.3%
  12. Total MDR resistance: 14/104 = 13.5%
  13. Results of the first survey of anti-tuberculosis drug resistance in Venezuela during 1998–1999.
  14. Resistance to drugs: Isoniazid (H), Rifampicin (R), Ethambutol (E), Streptomycin (S) in never treated and previously treated patients.