Gene | Function | Log2pH ratio | ||
---|---|---|---|---|
Acid up-regulated | pH 5.7/pH 7.0 | pH 7.0/pH 8.5 | pH 5.7/pH 8.5 | |
chaB | Regulator of Na+-Ca+/H+ antiporter | 0.80 | Â | Â |
chaC | Regulator of Na+-Ca+/H+ antiporter | 0.60 | -0.38 | Â |
copA | Copper-, silver-translocating P-type ATPase | 0.86 | -0.56 | Â |
cueR | Activator of copper-responsive regulon genes cueO and copA | 1.31 | -0.4 | 0.91 |
cusC | Silver and copper efflux | 0.44 | Â | 0.63 |
feoA | ferrous iron transport protein A | Â | 0.82 | 1.22 |
feoB | ferrous iron transport protein B | Â | 0.41 | 0.53 |
marR 1 | multiple antibiotic resistance protein | Â | 0.31 | Â |
mdtE | MdtEF-TolC multidrug resistance efflux transporter | 3.17 | -1.59 | 1.58 |
mdtF | MdtEF-TolC multidrug resistance efflux | 2.58 | -0.98 | 1.60 |
mdtG 1 | Multidrug resistance efflux transporter | 0.16 | Â | 0.25 |
mdtI 1 | multidrug transport protein | Â | 1.16 | 1.16 |
mdtJ 1 | multidrug transport protein | Â | 2.91 | 3.02 |
mdtL | Multidrug resistance efflux protein | Â | Â | 0.57 |
mgtA | Mg2+ transport | 0.48 | Â | 0.63 |
nhaA | Na+/H+ antiporter | 1.93 | -0.93 | 1.00 |
nhaB 1 | Na+/H+ antiporter | Â | 0.41 | 0.37 |
nikA | periplasmic binding protein for nickel | 0.7 | Â | 0.84 |
nikB | nickel transport | 0.50 | Â | 0.56 |
nikC | nickel transport | 0.70 | Â | 0.86 |
nikD | ATP-binding protein of nickel transport system | 0.60 | Â | 0.74 |
nikE | ATP-binding protein of nickel transport system | 0.45 | Â | 0.49 |
prc | carboxy-terminal protease for penicillin-binding protein 3 | 0.32 | Â | 0.37 |
Base up-regulated | ||||
acrA | acridine efflux pump | -0.34 | -0.35 | -0.69 |
acrB | acridine efflux pump | Â | Â | -0.42 |
acrR 2 | acrAB operon repressor | -0.93 | Â | -1.22 |
alx 2 | Putative metal transporter, homolog of terC (tellurium resistance) | Â | -0.57 | -0.52 |
ampC | beta-lactamase; penicillin resistance; penicillin-binding protein | -0.24 | Â | -0.12 |
atpA 2 | ATP synthase, F1 alpha-subunit | Â | Â | -0.66 |
atpC 2 | ATP synthase, F1 epsilon-subunit | Â | Â | -0.66 |
atpD 2 | ATP synthase, F1 beta-subunit | -0.35 | -0.36 | -0.71 |
atpF 2 | ATP synthase, F0 subunit b | Â | -0.46 | -0.51 |
atpG 2 | ATP synthase, F1 gamma-subunit | Â | Â | -0.66 |
atpH 2 | ATP synthase, F1 delta-subunit | Â | -0.42 | -0.58 |
atpI 2 | ATP synthase subunit | Â | Â | -0.53 |
chaA | Na+-Ca+/H+ antiporter | Â | -0.86 | -1.1 |
corA | Mg2+ transport, system I | 0.10 | Â | -0.39 |
cutA | divalent cation tolerance protein | -0.27 | Â | -0.3 |
dacA | D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 | -0.58 | Â | -0.65 |
dacC | D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 | 0.87 | -1.16 | Â |
dacD | penicillin binding protein 6b | -1.22 | Â | -0.90 |
emrA 1 | multidrug resistance secretion protein | -0.64 | Â | -0.11 |
mepA 1 | murein DD-endopeptidase, penicillin-insensitive | -0.68 | Â | -0.19 |
mreB 2 | regulator of ftsI, penicillin binding protein 3, septation function | -0.53 | Â | -0.44 |
mreC | rod shape-determining protein | -0.29 | Â | -0.39 |
napF | Fe-S ferredoxin-type protein | -0.59 | Â | -0.14 |
napG | ferredoxin-type protein | -0.39 | Â | -0.20 |
napH | ferredoxin-type protein | -0.37 | Â | -0.20 |