Table 3 gad regulon components showing pH dependence under oxygen limitation.
Gene | Function | Log2 Expression ratio | ||
|---|---|---|---|---|
| Â | Â | pH 5.7/pH 7.0 | pH 7.0/pH 8.5 | pH 5.7/pH 8.5 |
GadA region: 3650–3666 kb |  |  |  | |
slp | Outer membrane protein induced after carbon starvation | 3.47 | -1.82 | 1.64 |
dctR | Probable repressor of dctA dicarboxylate transporter gene | 2.60 | -1.00 | 1.59 |
yhiD | integral membrane protein related to MgtC. | 2.26 | -1.04 | 1.21 |
hdeB | Periplasmic chaperone of acid-denatured proteins | 0.79 | -0.55 | Â |
hdeA | Periplasmic chaperone of acid-denatured proteins | 0.74 | -0.50 | Â |
hdeD | Putative membrane transporter, H-NS repressed | 2.30 | -1.26 | 1.03 |
gadE | Required for stationary phase-induced, pH 5.5 growth medium-induced, and EvgA-induced acid resistance | 3.19 | -2.23 | 0.95 |
mdtE | MdtEF-TolC multidrug resistance efflux RND-type transporter; overexpression resistance to erythromycin, deoxycholate, octane and rhodamine | 3.17 | -1.59 | 1.58 |
mdtF | MdtEF-TolC multidrug resistance efflux RND-type transporter; overexpression resistance to erythromycin, deoxycholate, octane and rhodamine | 2.58 | -0.98 | 1.60 |
gadW | Positive AraC-type regulator of gadA and gadBC, in absence of gadX; repressor of gadX | 2.70 | -1.17 | 1.53 |
gadY | sRNA regulates gadX and gadY | 3.17 | -1.38 | 1.80 |
gadX | Positive transcriptional regulator of gadA and gadBC; repressed by HNS and GadW; stimulated by RpoS | 2.66 | -1.47 | 1.19 |
gadA | Glutamate decarboxylase isozyme | 4.89 | -3.46 | 1.43 |
GadB operon: 1567–1570 kb |  |  |  | |
gadB | Glutamate decarboxylase isozyme | 3.21 | -2.50 | Â |
gadC | Glutamate transporter | 3.73 | -2.44 | 1.29 |