Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implications

Table 3 Polymorphic sites among tuf-1 and tuf-2 from Brucella.

^$Nt position	12		36		141		183		198		219		345		378		511		609		936		1158
^#Bru↓\|Nt→	T	C	C	T	C	T	C	A	G	A	A	G	C	T	C	T	C	A	G	A	C	T	C	T
Bab 9–941	X		X		X		X		X		X		X		X		X		X		X		2	1
Bab b1	X		X		X		X		X		X		X		X		X		X		X			X
Bab b2	X		X		X		X		X		X		X		X		X		X		X		2	1
Bab b3	X		X		X		X		X		X		X		X		X		X		X		X
Bab b4	X		X		X		X		X		X		X		X		X		X		X		2	1
Bab b5	X		X		X		X		X		X		X		X		X		X		X		X
Bab b6	X		X		X		X		X		X		X		X		X		X		X		X
Bab b9	X		X		X		X		X		X		X		X		X		X		X		X
B. suis b1	X		X		X		X		X		X		X		X		X		X		X		X
B. suis b2	1	2	X		X		X		X		X		X		X			X	X		X		X
B. suis b3	1	2	X		X		X		X		X		X		X		X		X		X		X
B. suis b4	X		X		X		X		X		X		X		X		X		X		X		X
B. suis b5	1	2	X		X		X		X		X		X		X		X		X		X		X
Bmel b1	X			X		X		X		X		X		X		X	X		X			X	X
Bmel b2	X			X		X		X		X		X		X		X	X		X			X	X
Bmel b3	X			X		X		X		X		X		X		X	X		X			X	X
Bneo		X	X			X		X		X		X	X			X	X			X	X		X
B. ovis	X		X		X		X		X		X		X		X		X		X		X		X
B. canis	1	2	X		X		X		X		X		X		X		X		X		X		X
Seal	1	2	X		X		X		X			X	X			X	X		X		X		X
Dolphin	1	2	X		X		X		X			X	X			X	X		X		X		X
Porpoise	X		X		X		X		X			X	X			X	X		X		X		X

^$Nt = nucleotide; ^#Brucella strains, see Table 1; X = tuf-1 and tuf-2 have identical sequences; 1 = tuf-1 sequence only, 2 = tuf-2 sequence only. Polymorphic sites are in bold. tuf-1 and tuf-2 GenBank accession numbers are listed in Materials and methods.

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