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Figure 6 | BMC Microbiology

Figure 6

From: M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression

Figure 6

M. leprae upreglates Mcl-1 mRNA in THP-1 cells. THP-1 monocytes were infected with M. leprae or BCG at MOI-10 and RNA was harvested after 18 and 48 h of culture. mRNA was reverse transcribed and used for real-time PCR quantification of Mcl-1 and HuPO genes. Relative quantification data of 3 independent experiments calculated using the CT method is illustrated.

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