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Figure 4 | BMC Microbiology

Figure 4

From: M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression

Figure 4

M. leprae -, and BCG- induced time course expression of Bad and genes. THP-1 cells were infected with M. leprae, live and heat-killed BCG for 6, 18 and 48 h at MOI of 10 each. RNA was extracted, converted to cDNA and PCR carried out for Bad, Bak and β-actin genes. Graphs illustrate results obtained from the mean of 3 independent experiments. A, D. M. leprae-, B, E. live BCG- and C, F. heat killed BCG-induced Bad/βactin and Bak/βactin mRNA expression ratios; Spon (unstimulated cells).

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